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Lewis and Clark Trail ~From Sea to Shining Sea ~ Suggested Itinerary
Departure City - Destination City Miles Field Notes
Pittsburgh, PA - Cincinnati, Ohio 482 miles You are here

The Ohio River Scenic Highway

Wheeling, WV - Lewis landed here on September 7, 1803 on his newly built keelboat.  Visit Grave Creek Mound (one of the largest conical mounds constructed during the late Adena Period. Construction took place in successive stages from about 250-150 B.C.).

801 Jefferson Ave, Moundsville, WV 26041-2241

Maysville, Kentucky - Lewis must have recruited John Colter here on September 22nd or 23rd, 1803.  Later, in about 1808, Colter “discovered” Yellowstone Park area.
Visit the Mayville's Historic District, which is nestled along the banks of the Ohio River.  The Port of Maysville, an 1800s era river town. And just a short trip up the Buffalo Trace is the Washington Historic District; an authentic pioneer community of 1790s log cabins, shops and museums. 

216 Bridge St, Maysville, KY 41056-1208

Cincinnati, Ohio -Thomas Jefferson, who commissioned the expedition, asked Lewis to stop at Big Bone and collect bones of the giant mammals that were preserved in the salt lick. Visit Big Bone Lick State Park, Union, Kentucky near Cincinnati. 

3380 Beaver Rd, Union, KY 41091-8433


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