Paducah, Kentucky: The explorers reached what is now modern-day Paducah on November 11, 1803.

Fort Massac State Park, Metropolis, Illinois: When Lewis and Clark arrived at Fort Massac, Lewis hoped to find eight soldiers who had volunteered for the Corps of Discovery at South West Point, Tennessee, but they were not present. Lewis hired a local woodsman named George Drouillard, the son of a French father and Shawnee mother, to find the soldiers and report with them near St. Louis at the east bank of the Mississippi for the expedition west. Only two volunteers from Fort Massac met Captain Lewis's standards, and became members of the expedition. On November 13th, the Corps of Discovery left Fort Massac.

Suggest the 2.5-mile Hickory Nut Ridge Trail  is one not to miss, as it takes hikers along the scenic Ohio River.